Interstitial lung diseases (ILD) affect the tissue (interstitium) and space around the air sacs (alveoli), and differ from obstructive airway diseases. The group includes illnesses caused by inhaled substances, medications, infection, disease, malignancy and unknown causes (idiopathic). Causes of ILD include forms of pulmonary fibrosis and interstitial pneumonia, as well as ILDs associated with connective tissue diseases, exposure to environmental and occupational toxins, malignancy and idiopathic origin (unknown cause). The scarring associated with ILD affects a person’s ability to breathe and, subsequently, oxygenate the bloodstream.
Although scarring is mostly irreversible, medication therapies can slow further progression of lung damage. Pulmonary treatments and oxygen therapy can provide relief to patients. In severe cases, surgery and lung transplants can be an option for some ILD patients.
About Cleveland Clinic’s Interstitial Lung Disease Program
Cleveland Clinic’s Interstitial Lung Disease Program is a national leader in diagnostic and therapeutic procedures for ILD, a group of conditions that cause scarring to the lungs and resulting in limited oxygenation. As a high-volume center, Cleveland Clinic has extensive experience caring for the full range of types of ILD, including idiopathic pulmonary fibrosis, sarcoidosis, and connective tissue disease-related ILD, as well as rare types such as increasing pulmonary alveolar proteinosis (PAP) and lymphangioleiomyomatosis (LAM). We offer pulmonary rehabilitation, oxygen therapy and surgical procedures to maintain lung viability.
At Cleveland Clinic's Respiratory Institute, we provide world-class patient care by combining our strengths in clinical expertise, research and education. Serving nearly 90,000 patients annually, the Respiratory Institute’s unsurpassed expertise and experience attracts patients from all over the world who seek a definitive diagnosis and cutting-edge treatment, often for a rare or complex lung disorder. With more than 60 pulmonologists, allergists/immunologists and critical care specialists, the Respiratory Institute diagnoses and treats a wide range of lung, allergy and breathing-related conditions
About Our Doctors
Daniel Culver, D.O. is a staff physician in the Department of Pulmonary, Allergy, and Critical Care Medicine at Cleveland Clinic's main campus. He is board-certified in internal medicine with additional specialty certification in pulmonary medicine and critical care medicine.
Dr. Culver completed his residency in internal medicine, and a fellowship in pulmonary and critical care medicine at Cleveland Clinic. He earned his doctor of osteopathic medicine degree at the Ohio University College of Osteopathic Medicine in Athens, Ohio. After medical school, he did an osteopathic rotating internship at SouthPointe Hospital in Warrensville Heights, Ohio. Dr. Culver’s clinical interests include sarcoidosis, pulmonary alveolar proteinosis, critical care and interstitial lung diseases. Dr. Culver is a fellow of the American College of Chest Physicians and a member of several professional associations, including the American Thoracic Society, the American Osteopathic Association and the World Association of Sarcoidosis.
Joseph Parambil, M.D. is an associate staff member in the Department of Pulmonary, Allergy and Critical Care Medicine. He is also Assistant Professor of Medicine at Cleveland Clinic’s Lerner College of Medicine. Dr. Parambil is board-certified in internal medicine with additional specialty certification in pulmonary medicine and critical care medicine.
Dr. Parambil completed an internal medicine residency at Henry Ford Hospital in Detroit, as well as a fellowship in pulmonary and critical care medicine at Mayo Clinic in Rochester, Minn. He earned his medical degree from Semmelweis Medical University in Budapest, Hungary. Dr. Parambil completed a surgical internship at Frankford Hospital in Philadelphia. Dr. Parambil is a member of several professional societies, including the American College of Physicians, the American Society of Internal Medicine, American College of Chest Physicians, American Thoracic Society and Pulmonary Hypertension Association.
Join Drs. Culver and Parambil for this free web chat on Wednesday, November 7, from noon to 1 pm.