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Young-Onset Dementias
Thursday, June 6, 2013 - 12 Noon (Eastern Time)

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Brian Appleby, MD

  • Neurological Institute
  • Cleveland Clinic Lou Ruvo Center for Brain Health

Dementia is not a single disease. Rather, the term describes a loss of cognitive function (memory loss and/or speech problems) and behavioral problems (being unable to handle day-to-day tasks or tend to personal hygiene) that occur with many diseases. When these symptoms occur in younger patients (under age 65), it is called young onset dementia. The symptoms of young onset dementia may be subtle or increasing at an alarming rate. In either case, the first concern is to figure out what is causing the symptoms. Getting the correct diagnosis is of utmost importance in young patients because there is a higher possibility that the cause may be able to be treated when compared to dementia in older adults. Dr. Brian Appleby, Cleveland Clinic Lou Ruvo Center for Brain Health, can answer all of your questions about dementia and offer tips to preserve memory.


Brian Appleby, MD, joined Cleveland Clinic in 2011, having previously served as an Assistant Professor at Johns Hopkins University School of Medicine where he founded and directed the Johns Hopkins CJD Program and co-directed the Frontotemporal and Young-Onset Dementia Clinic. Dr. Appleby completed medical school at Georgetown University School of Medicine in Washington, D.C., and trained in psychiatry at Johns Hopkins Hospital in Baltimore, followed by a fellowship in geriatric psychiatry, also at Johns Hopkins. He is board-certified in psychiatry and geriatric psychiatry. He currently serves on the FDA Transmissible Spongiform Encephalopathy Advisory Committee and CJD Foundation Board of Directors. He specializes in the diagnosis and treatment of dementia, Creutzfeldt-Jakob and other prion diseases, and young-onset dementias.

To make an appointment with Dr. Appleby, or any of the Cleveland Clinic Lou Ruvo Center for Brain Health staff, please call 216.636.5860 or call toll-free at 866.588.2264. You can also visit us online at clevelandclinic.org/brainhealth

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